Who Do You Think You Are? Season 3

The third season of "Who Do You Think You Are?" debuts on NBC Friday night February 3rd at 8 PM Eastern and Pacific time and 7 PM Central. The popular show tells the family history of a popular celebrity each week. This year the stars to have their ancestries chronicled are Martin Sheen, Marisa Tomei, Blair Underwood, Reba McEntire, Rob Lowe, Helen Hunt, Rita Wilson, Edie Falco, Rashida Jones, Jerome Bettis, Jason Sudeikis and Paula Deen. 


Both genealogists and celebrity watchers will want to tune in.

Update on the new autosomal DNA test from Ancestry...

CeCe Moore reports that Ancestry.com claims to be making progress toward becoming a viable third provider of autosomal DNA testing to the genealogical community. 23andMe and Family Tree DNA (FTDNA) have provided these tests since early 2010. Check CeCe's recent blog post for the latest news: Your Genetic Genealogist: Update on the new autosomal DNA test from Ancestry... 


This development can be a very healthy development for those seeking to use DNA testing to identify distant cousins. However, this diversity of testing will, at least temporarily, further divide those who have tested at one lab from those who have tested at others. The main value of any kind of DNA testing for genealogical purposes is to be able to compare the results with others who have tested. If each lab maintains a proprietary database of its results it is very difficult for most genealogists to make meaning comparisons and to potentially make matches with those who have tested at other labs. Utilities that allow user friendly and meaningful comparisons of individuals, independent of which lab did the testing, will become increasingly important as the number of labs offering such tests increases. 


Such tools to compare results between laboratories will eventually emerge. However, testing companies may not see it as being to their competitive advantage to provide them. Consumers need to encourage the development of such tools -- whether they are provided by the testing companies or by independent entities.

23andMe Announces New Ancestry Ambassadors Group - Eastman's Online Genealogy Newsletter

As many of you may know, the DNA testing company 23andMe was formed primarily to provide customers with information about markers which might have an impact on health conditions. In February 2010 the company was the first to offer autosomal DNA testing to the masses when it introduced its Relative Finder product. Two months later Family Tree DNA introduced its Family Finder product. These two are still the premier, direct-to-consumer, autosomal DNA testing companies.


For those of you who are not familiar with DNA testing, there are currently three areas of a person's DNA that are being tested for genealogical purposes. During the first decade of this century, Y-chromosome testing was almost the only vehicle available to family historians. This was a good starting point for genealogists because it supplemented traditional surname research. It allowed researchers to trace paternal lines back many generations. However, its primary limitation is that only men have a Y-chromosome to be tested. Family Tree DNA
remains the premier company for Y-chromosome testing. The company offers the most extensive test to consumers--up to 111 markers. Equally important the company has the largest database against which comparisons can be made.


Mitochondrial DNA testing first became meaningful to genealogists when Family Tree DNA introduced its test of the full mitrochondria at an almost affordable price in 2009. Both sexes can test and the maternal line is what is followed by the results. This test result is even more stable over the centuries on a direct maternal line than is the result of a Y-chromosome test along a direct paternal line. 


Autosomal DNA provides information about all a person's ancestral lines--not just the direct paternal and maternal lines. However, that information only matches relatives who share ancestry within the last few generations. The probability that one would match with a given distant relative, who also has tested, can be seen in my prior blog post.


Recently I blogged about a short sighted decision by 23andMe that would have had a negative impact on genetic genealogists and Anne Wojcicki's mea culpa. I am happy to report that Anne is following up on her stated intention to listen to the concerns of the genetic genealogy community. Here is what Dick Eastman had to say about this new development:
23andMe Announces New Ancestry Ambassadors Group - Eastman's Online Genealogy Newsletter

"How to Do Everything: Genealogy," Third Edition by George Morgan

In a Facebook post yesterday, George G. Morgan announced that he had just received copies of his new third edition of his popular How to Do Everything: Genealogy which is was just published by McGraw Hill. Many of you know that George is an entertaining and informative speaker. If this edition meets the standards of his previous efforts, it will be well worth the purchase price.

Genetic testing in the United States may be hurt by the FDA’s confusing policies. - Slate Magazine

The linked article from Slate Magazine describes an issue that has the power to revolutionize our health care in the next decade. However, as the author describes, paternalistic views of the FDA and the medical profession may delay or dilute the develop personalized genomic medicine. We need to demand access to and control of the information about our bodies that is detailed in our DNA:

Genetic testing in the United States may be hurt by the FDA’s confusing policies. - Slate Magazine 

23andMe's "Netflix Moment"

23andMe recently experienced it's own "Netflix Moment". Those of you who are somewhat familiar with DNA testing may know that 23andMe offers two pricing plans for genetic genealogy customers. One is a subscription plan that cost $99 but comes bundled with a $9 per month fee. The other option is a flat rate charge of about $400. This test provides both genealogical and medical information. 23andMe originally started DNA testing to provide medically relevant information to its clients--especially those suffering from or at risk for Parkinson's. Autosomal DNA testing for genealogy matching was added in February, 2010.


Recently, 23andMe announced that it was pulling the plug on those customers who had not continued their subscription after the mandatory first year of membership. The way in which this was to be done not only would have denied those customers access to their results, it would have denied continuing customers the ability to continue to see their matches with former members who had chosen not to continue their subscriptions.


This announcement was greeted by a great outcry from genetic genealogists--much of which was circulated on the listserv of the International Society of Genetic Genealogy (ISOGG). Cece Moore, who blogs as Your Genetic Genealogist, was one of the leaders of the charge to convince 23andMe that this policy was not in the interest of its customer base of genealogists and therefore not in the interest of 23andMe. 


I am happy to report that 23andMe has just announced that this policy change is being revisited. Some of its aspects will not be implemented and others will be held in abeyance for 6 months until more sensitivity to the genealogical impact can be developed. Anne Wojcicki, co-founder of 23andMe, blogged:  


Let me begin by acknowledging that there are many things we could have done better over the years and there are especially things we could have done better with this recent incident involving the changes to our subscription.


- No changes will be made to any accounts until July 31, 2012


Anne also announced that she will be in contact with Cece Moore and others in the genealogical community to insure that the changes will be family history friendly. I'm sure Cece will be keeping us updated on her blog as this process develops. I am proud to say Cece will be my co-author on my next book project.

Goodbye California---Hello Tennessee

Friday Denise, RaggZ and I will depart our lovely home for the last 16 years in Morro Bay and head for new adventures in Nashville. Our new apartment will be part of a continuing care retirement complex located half a mile from the home of Jon, Shana, Noah and Simon. We will be an easy day's drive (or one hour flight) from Lee, Michelle, Jared, Jayson and Justin in the south Chicago suburbs; and a day and a half (or hour and a half flight) from Jason, Kindra, Alex and Devin in Virginia Beach. Debbie and Chris will be slightly farther away in NYC but are likely to return to Atlanta (CDC) in 2013 when mayor Bloomberg terms out. Debbie's position as Director of Special Projects reports to the Commissioner of Public and Mental Health who is a political appointee who serves at the pleasure of the mayor.

Our new address in Richland Place (http://www.richlandplace.com/) will be:

500 Elmington Ave, Apt 426
Nashville, TN 37205
Y'all come.

We should lower the average age among the 137 independent living units. We are very reluctantly leaving our window on the Pacific http://tours.tourfactory.com/tours/tour.asp?t=798456 but are looking forward to spending more time with our seven grandsons.

We haven't had time to get out Christmas cards this year. One of our New Year's resolutions is to get out greetings early in 2012 when we arrive in Nashville. Merry Christmas and Happy New Year.

Now I need to get back to packing boxes!

RootsMagic 5.0 Released

Today RootsMagic announced the release of version 5.0 of its popular genealogy program for Windows PCs.

For new customers the full version of this powerful program is $29. Current customers can upgrade for $19. A trial version is available for free download. I will be downloading the new version as soon as I finish this blog post. This has been my genealogy program of choice starting with its ancestor, FamilyOrigins. Click on the picture above or this link for details about this new version.


This would make a nice gift for those on your holiday list.

David Dowell's Adding DNA Testing Presentation

Linked below is a very nice review of my presentation on genetic genealogy a week ago in the Chicago area:

David Dowell's Adding DNA Testing Presentation - Chicago Genealogy | Examiner.com

Many Genes Associated With More Than One Disease

Grace Rattue reported on Monday in Medical News Today,

"According to investigators at the University of Edinburgh, individuals who carry specific genes, including some accountable for Parkinson's disease, some cancers and heart disease, may be at risk of developing other health problems. Although researchers have long suspected that different diseases are genetically associated, to date there has been insufficient systematic evidence to prove it. The study is published online in the American Journal of Human Genetics."

In that article the investigators state, 

"Showing that genes are linked to more than one disease is very important. We have shown that this is a common finding and not just an exception. Anyone who goes for genetic testing should be aware that in future, any information they receive about individual genes could have wider implications than they or the clinician immediately realize. They could also influence the risk of other conditions, so being aware of these wider effects is important."

For more information on this phenomena read Many Genes Associated With More Than One Disease.